4C T 2

Binding profile

4C-T-2 has affinity (K_i) for the 5-HT_1A (5,339 nM), 5-HT_1E (9,879 nM), 5-HT_2A (274.1 nM), 5-HT_2B (58.1 nM), 5-HT_2C (468.6 nM), 5-HT_5A (1,587 nM), 5-HT₇ (3,829), D₃ (1,273 nM), β₂-adrenergic (124.9 nM), I₁ (946.5 nM), and σ₁ (514 nM) receptors. The activity of 4C-T-2 at these sites has not been assayed, with the exception of the 5-HT_2A and 5-HT_2C receptors where it acts as a partial agonist.