4 phosphopantoate—beta alanine ligase

4-phosphopantoate—beta-alanine ligase (EC 6.3.2.36, phosphopantothenate synthetase, TK1686 protein) is an enzyme with systematic name (R)-4-phosphopantoate:beta-alanine ligase (AMP-forming). This enzyme catalyses the following chemical reaction

ATP + (R)-4-phosphopantoate + beta-alanine ⇌ AMP + diphosphate + (R)-4'-phosphopantothenate

The conversion of (R)-pantoate to (R)-4'-phosphopantothenate is part of the pathway leading to biosynthesis of 4'-phosphopantetheine.