4 hydroxybenzoyl CoA reductase

Updated on Jan 10, 2024

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EC number 1.3.7.9 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

In enzymology, a 4-hydroxybenzoyl-CoA reductase (EC 1.3.7.9) is an enzyme found in some bacteria and archaea that catalyzes the chemical reaction

benzoyl-CoA + acceptor + H₂O ⇌ 4-hydroxybenzoyl-CoA + reduced acceptor

The 3 substrates of this enzyme are benzoyl-CoA, acceptor, and H₂O, whereas its two products are 4-hydroxybenzoyl-CoA and reduced acceptor.

This enzyme participates in benzoate degradation via coa ligation.

Nomenclature

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is benzoyl-CoA:acceptor oxidoreductase. Other names in common use include:

4-hydroxybenzoyl-CoA reductase (dehydroxylating), and

4-hydroxybenzoyl-CoA:(acceptor) oxidoreductase.

References

4-hydroxybenzoyl-CoA reductase Wikipedia

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