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4 deoxy L threo 5 hexosulose uronate ketol isomerase

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EC number
  
5.3.1.17

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
37318-44-8

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase (EC 5.3.1.17) is an enzyme that catalyzes the chemical reaction

4-deoxy-L-threo-5-hexosulose uronate 3-deoxy-D-glycero-2,5-hexodiulosonate

Hence, this enzyme has one substrate, 4-deoxy-L-threo-5-hexosulose uronate, and one product, 3-deoxy-D-glycero-2,5-hexodiulosonate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is 4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase. This enzyme is also called 4-deoxy-L-threo-5-hexulose uronate isomerase. This enzyme participates in pentose and glucuronate interconversions.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1X8M, 1XRU, and 1YWK.

References

4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase Wikipedia


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