4 Phenylpiperidine

4-Phenylpiperidine is a chemical compound. It features a benzene ring bound to a piperidine ring.

4-Phenylpiperidine is the base structure for a variety of opioids, such as pethidine (meperidine), ketobemidone, alvimopan, loperamide, and diphenoxylate. Other pharmaceutical drugs derived from 4-phenylpiperdine include haloperidol, ropitoin, vesamicol, enefexine, and Altapizone.

A related compound is 4-benzylpiperidine, in which the rings are separated by a methylene bridge.