4 (hydroxymethyl)benzenesulfonate dehydrogenase

In enzymology, a 4-(hydroxymethyl)benzenesulfonate dehydrogenase (EC 1.1.1.257) is an enzyme that catalyzes the chemical reaction

4-(hydroxymethyl)benzenesulfonate + NAD⁺ ⇌ 4-formylbenzenesulfonate + NADH + H⁺

Thus, the two substrates of this enzyme are 4-(hydroxymethyl)benzenesulfonate and NAD⁺, whereas its 3 products are 4-formylbenzenesulfonate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 4-(hydroxymethyl)benzenesulfonate:NAD⁺ oxidoreductase. This enzyme participates in 2,4-dichlorobenzoate degradation.