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4′-Ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) is a flavor enhancer for fermented soy sauce produced by Yamasa Corporation.
It also has activity against HIV in animal models.
Biological activity
EFdA is a nucleoside analogue reverse transcriptase inhibitor that unlike other such inhibitors, inhibits HIV through multiple mechanisms. providing rapid suppression of the virus, when tested in macaques and mice. Nevertheless, there are HIV strains resistant to EFdA and research is ongoing.
References
4′-Ethynyl-2-fluoro-2′-deoxyadenosine Wikipedia(Text) CC BY-SA