4,4' Diapophytoene desaturase

4,4'-Diapophytoene desaturase (EC 1.3.8.2, dehydrosqualene desaturase, CrtN, 4,4'-diapophytoene:FAD oxidoreductase) is an enzyme with systematic name 15-cis-4,4'-diapophytoene:FAD oxidoreductase. This enzyme catalyses the following chemical reaction

15-cis-4,4'-diapophytoene + 4 FAD ⇌ all-trans-4,4'-diapolycopene + 4 FADH2 (overall reaction) (1a) 15-cis-4,4'-diapophytoene + FAD ⇌ all-trans-4,4'-diapophytofluene + FADH2 (1b) all-trans-4,4'-diapophytofluene + FAD ⇌ all-trans-4,4'-diapo-zeta-carotene + FADH2 (1c) all-trans-4,4'-diapo-zeta-carotene + FAD ⇌ all-trans-4,4'-diaponeurosporene + FADH2 (1d) all-trans-4,4'-diaponeurosporene + FAD ⇌ all-trans-4,4'-diapolycopene + FADH2

This enzyme is typical of Staphylococcus aureus and some other bacteria such as Heliobacillus sp.