Samiksha Jaiswal

4' Fluorocannabidiol

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Legal status  CA: Schedule II
PubChem CID  76285390
Formula  C21H29FO2
CAS Number  1619228-89-5
ChemSpider  58191436
Molar mass  332.46 g·mol
4'-Fluorocannabidiol

4'-Fluorocannabidiol (also known as HUF-101 and 4'-F-CBD) is a fluorinated cannabidiol derivative that has more potent anxiolytic, antidepressant, antipsychotic and anti-compulsive activity in mice compared to its parent compound. It was first synthesized in 2016, alongside 10-fluorocannabidiol diacetate and 8,9-dihydro-7-fluorocannabidiol.

Synthesis

4'-fluoro-cannabidiol was synthesized from isolated cannabidiol by putting it in dry dichloromethane and adding 1-fluoropyridinium triflate.

References

4'-Fluorocannabidiol Wikipedia


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