Samiksha Jaiswal (Editor)

4' Fluorocannabidiol

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Legal status
  
CA: Schedule II

PubChem CID
  
76285390

Formula
  
C21H29FO2

CAS Number
  
1619228-89-5

ChemSpider
  
58191436

Molar mass
  
332.46 gĀ·mol

4'-Fluorocannabidiol

4'-Fluorocannabidiol (also known as HUF-101 and 4'-F-CBD) is a fluorinated cannabidiol derivative that has more potent anxiolytic, antidepressant, antipsychotic and anti-compulsive activity in mice compared to its parent compound. It was first synthesized in 2016, alongside 10-fluorocannabidiol diacetate and 8,9-dihydro-7-fluorocannabidiol.

Synthesis

4'-fluoro-cannabidiol was synthesized from isolated cannabidiol by putting it in dry dichloromethane and adding 1-fluoropyridinium triflate.

References

4'-Fluorocannabidiol Wikipedia