3beta(or 20alpha) hydroxysteroid dehydrogenase

Updated on Oct 03, 2024

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EC number 1.1.1.210 IntEnz IntEnz view ExPASy NiceZyme view		CAS number 82869-26-9 BRENDA BRENDA entry KEGG KEGG entry

In enzymology, a 3-β(or 20-α)-hydroxysteroid dehydrogenase (EC 1.1.1.210) is an enzyme that catalyzes the chemical reaction

5α-androstan-3β,17β-diol + NADP⁺ ⇌ 17β-hydroxy-5α-androstan-3-one + NADPH + H⁺

This enzyme possesses the combined activities of the 3-β-hydroxysteroid dehydrogenase/Δ-5-4 isomerase and 20-α-hydroxysteroid dehydrogenase enzymes.

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