EC number 1.1.1.52 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9028-57-3 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a 3alpha-hydroxycholanate dehydrogenase (EC 1.1.1.52) is an enzyme that catalyzes the chemical reaction
3alpha-hydroxy-5beta-cholanate + NAD+Thus, the two substrates of this enzyme are 3alpha-hydroxy-5beta-cholanate and NAD+, whereas its 3 products are 3-oxo-5beta-cholanate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3alpha-hydroxy-5beta-cholanate:NAD+ oxidoreductase. This enzyme is also called alpha-hydroxy-cholanate dehydrogenase.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1IHI.
References
3alpha-hydroxycholanate dehydrogenase Wikipedia(Text) CC BY-SA