3 Succinoylsemialdehyde pyridine dehydrogenase

3-Succinoylsemialdehyde-pyridine dehydrogenase (EC 1.2.1.83) is an enzyme with systematic name 4-oxo-4-(pyridin-3-yl)butanal:NADP⁺ oxidoreductase. This enzyme catalyses the following chemical reaction

4-oxo-4-(pyridin-3-yl)butanal + NADP⁺ + H₂O ⇌ 4-oxo-4-(pyridin-3-yl)butanoate + NADPH + H⁺

The enzyme has been characterized from the soil bacterium Pseudomonas sp. HZN6.