3 Oxo 5,6 dehydrosuberyl CoA semialdehyde dehydrogenase

3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase (EC 1.17.1.7, paaZ (gene)) is an enzyme with systematic name 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde:NADP⁺ oxidoreductase. This enzyme catalyses the following chemical reaction

3-oxo-5,6-dehydrosuberyl-CoA semialdehyde + NADP⁺ + H₂O ⇌ 3-oxo-5,6-dehydrosuberyl-CoA + NADPH + H⁺

The enzyme from Escherichia coli is a bifunctional protein that also acts as EC 3.7.1.16, oxepin-CoA hydrolase.