Puneet Varma (Editor)

3 Monoacetylmorphine

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Routes of administration
  
Intravenous

CAS Number
  
5140-28-3

Molar mass
  
327.1471 g/mol

ATC code
  
none

PubChem CID
  
5462504

3-Monoacetylmorphine httpsuploadwikimediaorgwikipediacommonsthu

Legal status
  
AU: S9 (Prohibited) UK: Class A US: Schedule I

Synonyms
  
3-Acetylmorphine, O(3)-monoacetylmorphine

3-Monoacetylmorphine (3-MAM) or 3-acetylmorphine is a less active metabolite of heroin (diacetylmorphine), the other two being morphine and more active 6-monoacetylmorphine (6-MAM).

Because of the acetyl-group in 3-position, 3-MAM has relatively weak affinity to μ-opioid receptors.

As 3-O-acetylmorphine-6-O-sulfate (C19H23NO7S), where 6-OH is changed to 6-O-SO3, it can act as potent, centrally acting morphine derivative and has important analgesic properties.

References

3-Monoacetylmorphine Wikipedia