Routes ofadministration Intravenous CAS Number 5140-28-3 Molar mass 327.1471 g/mol | ATC code none PubChem CID 5462504 | |
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Legal status AU: S9 (Prohibited)UK: Class AUS: Schedule I Synonyms 3-Acetylmorphine, O(3)-monoacetylmorphine | ||
3-Monoacetylmorphine (3-MAM) or 3-acetylmorphine is a less active metabolite of heroin (diacetylmorphine), the other two being morphine and more active 6-monoacetylmorphine (6-MAM).
Because of the acetyl-group in 3-position, 3-MAM has relatively weak affinity to μ-opioid receptors.
As 3-O-acetylmorphine-6-O-sulfate (C19H23NO7S), where 6-OH is changed to 6-O-SO3, it can act as potent, centrally acting morphine derivative and has important analgesic properties.
References
3-Monoacetylmorphine Wikipedia(Text) CC BY-SA