3 Ketosteroid 9alpha monooxygenase

Updated on Dec 20, 2024

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EC number 1.14.13.142 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

3-ketosteroid 9alpha-monooxygenase (EC 1.14.13.142, KshAB, 3-ketosteroid 9alpha-hydroxylase) is an enzyme with systematic name androsta-1,4-diene-3,17-dione,NADH:oxygen oxidoreductase (9alpha-hydroxylating). This enzyme catalyses the following chemical reaction

androsta-1,4-diene-3,17-dione + NADH + H⁺ + O₂ ⇌ 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD⁺ + H₂O

3-Ketosteroid 9alpha-monooxygenase is involved in the cholesterol degradation in several bacterial pathogens.

References

3-Ketosteroid 9alpha-monooxygenase Wikipedia

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