3 Isopropylmalate dehydrogenase

Updated on Dec 20, 2024

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EC number 1.1.1.85 IntEnz IntEnz view ExPASy NiceZyme view		CAS number 9030-97-1 BRENDA BRENDA entry KEGG KEGG entry

3-Isopropylmalate dehydrogenase (EC 1.1.1.85) is an enzyme that catalyzes the chemical reactions

(2R,3S)-3-isopropylmalate + NAD⁺ ⇌ 4-methyl-2-oxopentanoate + CO₂ + NADH(2R,3S)-3-isopropylmalate + NAD⁺ ⇌ (2S)-2-isopropyl-3-oxosuccinate + H⁺ + NADH(2S)-2-isopropyl-3-oxosuccinate + H⁺ ⇌ 4-methyl-2-oxopentanoate + CO₂

References

3-Isopropylmalate dehydrogenase Wikipedia

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