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3 Bromocytisine

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CAS Number  207390-14-5
ChemSpider  21376088
3D model (Jmol)  Interactive image
PubChem CID  15519735
Formula  C11H13BrN2O
Molar mass  269.14 g/mol
3-Bromocytisine httpsuploadwikimediaorgwikipediacommonsthu

3-Bromocytisine is a derivative of the toxic alkaloid cytisine that acts as a highly potent agonist at neural nicotinic acetylcholine receptors, binding primarily to the α4β2 and α7 subtypes. 3-Bromocytisine is a full agonist at the α7 subtype while it is only a partial agonist at α4β2, but has an extremely strong binding affinity at α4β2 with 200-fold selectivity for α4β2 over α7. In animal studies 3-bromocytisine stimulates the release of dopamine and noradrenaline and increases locomotor activity.

References

3-Bromocytisine Wikipedia


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