Suvarna Garge (Editor)

3 Bromocytisine

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CAS Number
  
207390-14-5

ChemSpider
  
21376088

3D model (Jmol)
  
Interactive image

PubChem CID
  
15519735

Formula
  
C11H13BrN2O

Molar mass
  
269.14 g/mol

3-Bromocytisine httpsuploadwikimediaorgwikipediacommonsthu

3-Bromocytisine is a derivative of the toxic alkaloid cytisine that acts as a highly potent agonist at neural nicotinic acetylcholine receptors, binding primarily to the α4β2 and α7 subtypes. 3-Bromocytisine is a full agonist at the α7 subtype while it is only a partial agonist at α4β2, but has an extremely strong binding affinity at α4β2 with 200-fold selectivity for α4β2 over α7. In animal studies 3-bromocytisine stimulates the release of dopamine and noradrenaline and increases locomotor activity.

References

3-Bromocytisine Wikipedia