3 (3 hydroxyphenyl)propanoate hydroxylase

3-(3-hydroxyphenyl)propanoate hydroxylase (EC 1.14.13.127, mhpA (gene)) is an enzyme with systematic name 3-(3-hydroxyphenyl)propanoate,NADH:oxygen oxidoreductase (2-hydroxylating). This enzyme catalyses the following chemical reaction

(1) 3-(3-hydroxyphenyl)propanoate + NADH + H⁺ + O₂ ⇌ 3-(2,3-dihydroxyphenyl)propanoate + H₂O + NAD⁺(2) (2E)-3-(3-hydroxyphenyl)prop-2-enoate + NADH + H⁺ + O₂ ⇌ (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + H₂O + NAD⁺

3-(3-hydroxyphenyl)propanoate hydroxylase is a flavoprotein (FAD).