3 (cis 5,6 dihydroxycyclohexa 1,3 dien 1 yl)propanoate dehydrogenase

3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase (EC 1.3.1.87, hcaB (gene), cis-dihydrodiol dehydrogenase, 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase) is an enzyme with systematic name 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate:NAD⁺ oxidoreductase. This enzyme catalyses the following chemical reaction

(1) 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD⁺ ⇌ 3-(2,3-dihydroxyphenyl)propanoate + NADH + H⁺ (2) (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD⁺ ⇌ (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + NADH + H⁺

This enzyme catalyses a step in indegradation of phenylpropanoid compounds.