23S rRNA (cytidine1920 2' O) methyltransferase

23S rRNA (cytidine¹⁹²⁰-2'-O)-methyltransferase (EC 2.1.1.226, TlyA) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (cytidine¹⁹²⁰-2'-O)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + cytidine¹⁹²⁰ in 23S rRNA ⇌ S-adenosyl-L-homocysteine + 2'-O-methylcytidine¹⁹²⁰ in 23S rRNA

This is a bifunctional enzyme from Mycobacterium tuberculosis.