23S rRNA (guanine1835 N2) methyltransferase

Updated on Nov 08, 2023

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EC number 2.1.1.174 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

23S rRNA (guanine¹⁸³⁵-N²)-methyltransferase (EC 2.1.1.174, ygjO (gene), rlmG (gene), ribosomal RNA large subunit methyltransferase G) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine¹⁸³⁵-N²)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + guanine¹⁸³⁵ in 23S rRNA ⇌ S-adenosyl-L-homocysteine + N²-methylguanine¹⁸³⁵ in 23S rRNA

The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate.

References

23S rRNA (guanine1835-N2)-methyltransferase Wikipedia

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