The 2011 Premier League Knock-Out Cup was contested throughout the 2011 Premier League Season. The Reigning champions from 2010, the Newcastle Diamonds were narrowly eliminated by the Glasgow Tigers in the semi-final stages. However the competition was won by the Newport Wasps who defeated the league champions Glasgow Tigers, 106-74 on aggregate.
Round 1
The draw for the 2011 Premier League KOC was taking at the 2010 AGM. 12 teams were drawn against each other, with 2 teams receiving 'byes' into the Quarter Finals. These two teams that received a bye were the Berwick Bandits and the Newport Wasps. The Kings Lynn Stars were originally going to face the Somerset Rebels, however due to their election to compete in the Elite League, the new premier league side, the Plymouth Devils would now face the Rebels. As Scunthorpe and Ipswich tied 90-90 on aggregate, their matches were replayed.