2010 Western and Southern Financial Group Masters – Doubles

Daniel Nestor and Nenad Zimonjić were the defending champions, but they lost to František Čermák and Michal Mertiňák 7–5, 6–2 in the first round.
Bob Bryan and Mike Bryan won in the final against Mahesh Bhupathi and Max Mirnyi, 6–3, 6–4.