| Albert Montañés|
6–2, 1–2, RET.
| Gaël Monfils|
Jérémy Chardy was the defending champion; however, he lost to Daniel Gimeno-Traver in the first round.
Albert Montañés became the new champion, after his victory against Gaël Monfils in the final. Monfils retired during the second set.
2010 MercedesCup – Singles Wikipedia
The top four seeds receive a bye into the second round.