2010 FC Sibir Novosibirsk season

The 2010 FC Sibir Novosibirsk season was the clubs first, and only, season in the Russian Premier League, the highest tier of football in Russia. They finished the season in 16th position and were relegated back to the Russian First Division after one season. Sibir were also defeated by Spartak Moscow in the 2010–11 Russian Cup at the Round of 16 stage, and by PSV Eindhoven in the Play-off round of the 2010–11 UEFA Europa League.