| 6–2, 7–6|
| Victoria Azarenka
2008 French Open – Mixed Doubles Wikipedia
Nathalie Dechy and Andy Ram were the defending champions, but lost in the first round to Dominika Cibulková and Gaël Monfils.
Victoria Azarenka and Bob Bryan won in the final 6–2, 7–6(7–4), against Katarina Srebotnik and Nenad Zimonjić.