2006 US Open – Wheelchair Women's Doubles

The United States Open Tennis Championships is a hardcourt tennis tournament held annually at Flushing Meadows, starting on the last Monday in August and lasting for two weeks. The tournament consists of five main championship events: men's and women's singles, men's and women's doubles, and mixed doubles, with additional tournaments for seniors, juniors, and wheelchair players.

In 2006, the wheelchair women's doubles event was won by Jiske Griffioen and Esther Vergeer, both of the Netherlands, who beat Korie Homan and Maaike Smit, also of the Netherlands, 6-4, 6-4 in the final.