| Serena Williams|
2–6, 6–3, 6–0
| Lindsay Davenport|
2005 Australian Open – Women's Singles Wikipedia
Justine Henin was the defending champion, but she could not compete this year due to a knee injury.
Serena Williams won her second Australian Open title despite being three match points down in the third set of semifinals against Maria Sharapova, defeating World No. 1 and compatriot Lindsay Davenport in the final.
This event is notable for the first Grand Slam appearances from future World No. 1 and Grand Slam Champion Ana Ivanovic and double Grand Slam champion Li Na.