President: Thabo Mbeki
Deputy President: Jacob Zuma
March
18 – The Department of Health declines the offer of a large donation of HIV test kits made by Guardian Scientific Africa Incorporated.
April
5 – George Bizos is awarded the 2001 International Trial Lawyer Prize of the Year by the International Academy of Trial Lawyers.
11 – Pfizer Inc. agrees to supply AIDS patients attending public hospitals with an unlimited two-year supply of Fluconazole.
30 – South Africa and India sign a declaration of intent on co-operation in health and medicine.
June
11 – The Maloti-Drakensberg Transfrontier Conservation Area is signed into existence.
12–15 – President of South Africa Thabo Mbeki undertakes a state visit to the United Kingdom.
September
1–8 – Durban hosts the World Conference against Racism.
October
4 – The first 40 of a planned 1000 elephants, including 3 breeding herds, are translocated from the over-populated Kruger National Park to the war-ravaged Limpopo National Park.
9 – The second South African National Census takes place.
The name of the Gaza-Kruger-Gonarezhou Transfrontier Park is changed to the Great Limpopo Transfrontier Park.
December
4 – Marike de Klerk, ex-wife of former State President Frederik Willem de Klerk, is murdered in her flat in Cape Town.
Unknown date
The New National Party withdraws from the Democratic Alliance.
13 August – Fanie du Plessis (71), South African athlete. (b. 1930)
The first of seventeen Class 7E3, Series 1 and Series 2 dual-cab electric locomotives, rebuilt by Spoornet to single-cabs, enter service reclassified to Class 7E4.
4 March – Ian Syster wins his first national title in the men's marathon, clocking 2:13:30 in Durban.
2001 in South Africa Wikipedia (Text) CC BY-SA