EC number 1.2.7.2 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 37251-04-0 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a 2-oxobutyrate synthase (EC 1.2.7.2) is an enzyme that catalyzes the chemical reaction
2-oxobutanoate + CoA + oxidized ferredoxinThe 3 substrates of this enzyme are 2-oxobutanoate, CoA, and oxidized ferredoxin, whereas its 3 products are propanoyl-CoA, CO2, and reduced ferredoxin.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is 2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propanoylating). Other names in common use include alpha-ketobutyrate-ferredoxin oxidoreductase, 2-ketobutyrate synthase, alpha-ketobutyrate synthase, 2-oxobutyrate-ferredoxin oxidoreductase, and 2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propionylating). This enzyme participates in propanoate metabolism.