2 dehydropantoate aldolase

In enzymology, a 2-dehydropantoate aldolase (EC 4.1.2.12) is an enzyme that catalyzes the chemical reaction

2-dehydropantoate ⇌ 3-methyl-2-oxobutanoate + formaldehyde

Hence, this enzyme has one substrate, 2-dehydropantoate, and two products, 3-methyl-2-oxobutanoate and formaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-dehydropantoate formaldehyde-lyase (3-methyl-2-oxobutanoate-forming). Other names in common use include ketopantoaldolase, and 2-dehydropantoate formaldehyde-lyase.