2 coumarate reductase

In enzymology, a 2-coumarate reductase (EC 1.3.1.11) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are 3-(2-hydroxyphenyl)propanoate and NAD⁺, whereas its 3 products are 2-coumarate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase. This enzyme is also called melilotate dehydrogenase. This enzyme participates in phenylalanine metabolism.