Neha Patil (Editor)

2 Formylpyridine

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Related compounds  Picolinic acid
2-Formylpyridine

2-Formylpyridine, also commonly called pyridine-2-carboxaldehyde, is an organic compound with the formula NC5H4CHO. It is a colorless oily liquid with a distinctive odor. Older samples are often brown-colored owing to impurities. It serves as a precursor to other compounds of interest in coordination chemistry and pharmaceuticals. Pyridine aldehydes are typically prepared by oxidation of the hydroxymethyl- or methylpyridines.

Reactions and uses

The drug pralidoxime can be produced from 2-formylpyridine.

The aldehyde functional group is subject to nucleophilic attack, specifically by amines to form Schiff bases, which serve as bidentate ligands. Iminopyridine complexes can be remarkably robust.

References

2-Formylpyridine Wikipedia


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