EC number 1.1.1.268 BRENDA BRENDA entry KEGG KEGG entry | IntEnz IntEnz view ExPASy NiceZyme view MetaCyc | |
In enzymology, a 2-(R)-hydroxypropyl-CoM dehydrogenase (EC 1.1.1.268) is an enzyme that catalyzes the chemical reaction
2-(R)-hydroxypropyl-CoM + NAD+Thus, the two substrates of this enzyme are 2-(R)-hydroxypropyl-CoM and NAD+, whereas its 3 products are 2-oxopropyl-CoM, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-[2-(R)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase. This enzyme is also called 2-(2-(R)-hydroxypropylthio)ethanesulfonate dehydrogenase.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2CFC.
References
2-(R)-hydroxypropyl-CoM dehydrogenase Wikipedia(Text) CC BY-SA