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2,4,5 Trihydroxyamphetamine

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2,4,5-Trihydroxyamphetamine

2,4,5-Trihydroxyamphetamine (THM) is a neurotoxin and a metabolite of MDMA. It comes from the ring-hydroxylation of 3,4-methylenedioxyamphetamine (MDA).

In one paper, it was shown to reduce hippocampal tryptophan hydroxylase activity by 54% after short-term treatment. In another study, it was shown to significantly reduce striatal tyrosine hydroxylase activity.

References

2,4,5-Trihydroxyamphetamine Wikipedia


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