26 February - Fernand Georges is appointed to the Council of State.
2 March – Luxembourg City is agreed to remain one of the seats of the European Union as part of the negotiations over the Merger Treaty.
20 March – Representing Luxembourg, France Gall wins the Eurovision Song Contest 1965 with the song Poupée de cire, poupée de son.
12 June – A law is signed governing industrial relations, making arbitration compulsory.
23 August – Antoine Krier replaces Nicolas Biever in the government, after Biever's death the previous month.
30 December – Compulsory national service is reduced to six months.
14 January – Désirée Nosbusch, singer and presenter of Eurovision Song Contest 1984, the last time Luxembourg hosted the Eurovision Song Contest.
22 October – Georges Lentz, composer
4 December - Françoise Groben, cellist
10 December – Alain Hamer, football referee
15 July – Nicolas Biever, politician and trade unionist
23 September – Emile Maar, Resistance leader
9 October – François Simon, politician
1965 in Luxembourg Wikipedia (Text) CC BY-SA