1961 St. Louis Cardinals (NFL) season

The 1961 St. Louis Cardinals season was the team's 42nd season in the National Football League (NFL) and their second in St. Louis. The team improved on their previous year's 6–5–1 record, winning seven games. Despite the improvement, they finished fourth in the seven-team Eastern Conference and failed to qualify for the playoffs (NFL title game) for the thirteenth consecutive season. The Cardinals were led by fourth-year head coach Pop Ivy, who was replaced after a 5–7 start by the tandem of Chuck Drulis, Ray Prochaska, and Ray Willsey.

This was the final season of ownership by Violet Bidwill Wolfner, who died in January 1962 at age 62.