1912 U.S. National Championships – Women's Singles

Mary Browne defeated Eleonora Sears 6–4, 6–2 in the final of the 1912 U.S. Women's National Singles Championship. The event was held at the Philadelphia Cricket Club in Philadelphia, Pennsylvania, USA from June 10 through June 15, 1912. The defending champion, Hazel Hotchkiss Wightman, did not participate in this edition and therefore no challenge round was played.