16S rRNA (guanine1207 N2) methyltransferase

16S rRNA (guanine¹²⁰⁷-N²)-methyltransferase (EC 2.1.1.172, m2G1207 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (guanine¹²⁰⁷-N²)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + guanine¹²⁰⁷ in 16S rRNA ⇌ S-adenosyl-L-homocysteine + N²-methylguanine¹²⁰⁷ in 16S rRNA

The enzyme reacts well with 30S subunits reconstituted from 16S RNA transcripts and 30S proteins but is almost inactive with the corresponding free RNA.