16S rRNA (cytidine1409 2' O) methyltransferase

16S rRNA (cytidine¹⁴⁰⁹-2'-O)-methyltransferase (EC 2.1.1.227, TlyA) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (cytidine¹⁴⁰⁹-2'-O)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + cytidine¹⁴⁰⁹ in 16S rRNA ⇌ S-adenosyl-L-homocysteine + 2'-O-methylcytidine1⁴⁰⁹ in 16S rRNA

The bifunctional enzyme from Mycobacterium tuberculosis.