16S rRNA (cytosine1407 C5) methyltransferase

16S rRNA (cytosine¹⁴⁰⁷-C⁵)-methyltransferase (EC 2.1.1.178, RNA m5C methyltransferase YebU, RsmF, YebU) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (cytosine¹⁴⁰⁷-C⁵)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + cytosine¹⁴⁰⁷ in 16S rRNA ⇌ S-adenosyl-L-homocysteine + 5-methylcytosine¹⁴⁰⁷ in 16S rRNA

The enzyme specifically methylates cytosine¹⁴⁰⁷ at C⁵ in 16S rRNA.