Puneet Varma

10 Deacetylbaccatin

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Formula  C29H36O10
Appearance  colorless solid
Molar mass  544.59 g/mol
10-Deacetylbaccatin httpsuploadwikimediaorgwikipediacommonsthu

10-Deacetylbaccatins are a series of closely related natural organic compounds isolated from the Pacific yew tree (Taxus brevifolia) and related species. 10-Deacetylbaccatin III is a precursor to the anti-cancer drug docetaxel (Taxotere).

10-deacetylbaccatin III 10-O-acetyltransferase converts 10-deacetylbaccatin to baccatin III:

acetyl-CoA + 10-deacetylbaccatin III ⇌ CoA + baccatin III

References

10-Deacetylbaccatin Wikipedia


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