1 Deoxy 11beta hydroxypentalenate dehydrogenase

1-deoxy-11beta-hydroxypentalenate dehydrogenase (EC 1.1.1.340, 1-deoxy-11beta-hydroxypentalenic acid dehydrogenase, ptlF (gene), penF (gene name)) is an enzyme with systematic name 1-deoxy-11beta-hydroxypentalenate:NAD⁺ oxidoreductase. This enzyme catalyses the following chemical reaction

1-deoxy-11beta-hydroxypentalenate + NAD⁺ ⇌ 1-deoxy-11-oxopentalenate + NADH + H⁺

This enzyme from the bacterium Streptomyces avermitilis participates in pentalenolactone biosynthesis.