Trisha Shetty (Editor)

1,2 dihydroxy 6 methylcyclohexa 3,5 dienecarboxylate dehydrogenase

Updated on
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
EC number
KEGG  KEGG entry
IntEnz  IntEnz view
ExPASy  NiceZyme view
MetaCyc  metabolic pathway

In enzymology, a 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase (EC is an enzyme that catalyzes the chemical reaction

1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+ 3-methylcatechol + NADH + CO2

Thus, the two substrates of this enzyme are 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate and NAD+, whereas its 3 products are 3-methylcatechol, NADH, and CO2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate:NAD+ oxidoreductase (decarboxylating). This enzyme participates in toluene and xylene degradation.


1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase Wikipedia