(R) citramalate synthase

Updated on Sep 24, 2024

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EC number 2.3.1.182 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

(R)-citramalate synthase (EC 2.3.1.182, CimA) is an enzyme. This enzyme catalyses the following chemical reaction

acetyl-CoA + pyruvate + H₂O ⇌ CoA + (2R)-2-hydroxy-2-methylbutanedioate

This enzyme participates in a novel pyruvate pathway for isoleucine biosynthesis.

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