EC number 2.7.7.42 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9077-66-1 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a [glutamate—ammonia-ligase] adenylyltransferase (EC 2.7.7.42) is an enzyme that catalyzes the chemical reaction
ATP + [L-glutamate:ammonia ligase (ADP-forming)]Thus, the two substrates of this enzyme are ATP and L-glutamate:ammonia ligase (ADP-forming), whereas its two products are diphosphate and [[adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]]].
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ATP:[L-glutamate:ammonia ligase (ADP-forming)] adenylyltransferase. Other names in common use include glutamine-synthetase adenylyltransferase, ATP:glutamine synthetase adenylyltransferase, and adenosine triphosphate:glutamine synthetase adenylyltransferase.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1V4A.