Samiksha Jaiswal (Editor)

(S) usnate reductase

Updated on
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
EC number
IntEnz  IntEnz view
ExPASy  NiceZyme view
CAS number  77237-99-1
KEGG  KEGG entry

In enzymology, a (S)-usnate reductase (EC is an enzyme that catalyzes the chemical reaction

(6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6- methyl-2,4-cyclohexadien-1-one + NAD+ (S)-usnic acid + NADH + H+

In the reverse direction, (S)-usnate is reduced by NADH with cleavage of the ether bond to form a 7-hydroxy group.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is reduced-(S)-usnate:NAD+ oxidoreductase (ether-bond-forming). This enzyme is also called L-usnic acid dehydrogenase.


(S)-usnate reductase Wikipedia