Samiksha Jaiswal (Editor)

(S) limonene 7 monooxygenase

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EC number
  
1.14.13.49

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
122653-75-2

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a (S)-limonene 7-monooxygenase (EC 1.14.13.49) is an enzyme that catalyzes the chemical reaction

(-)-(S)-limonene + NADPH + H+ + O2 (-)-perillyl alcohol + NADP+ + H2O

The 4 substrates of this enzyme are (-)-(S)-limonene, NADPH, H+, and O2, whereas its 3 products are (-)-perillyl alcohol, NADP+, and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is (S)-limonene,NADPH:oxygen oxidoreductase (7-hydroxylating). Other names in common use include (-)-limonene 7-monooxygenase, (-)-limonene hydroxylase, (-)-limonene monooxygenase, and (-)-limonene,NADPH:oxygen oxidoreductase (7-hydroxylating). This enzyme participates in monoterpenoid biosynthesis and limonene and pinene degradation. It employs one cofactor, heme.

References

(S)-limonene 7-monooxygenase Wikipedia