|EC number 188.8.131.52|
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|CAS number 37250-96-7|
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KEGG KEGG entry
In enzymology, a (R)-dehydropantoate dehydrogenase (EC 184.108.40.206) is an enzyme that catalyzes the chemical reaction(R)-4-dehydropantoate + NAD+ + H2O
The 3 substrates of this enzyme are (R)-4-dehydropantoate, NAD+, and H2O, whereas its 3 products are (R)-3,3-dimethylmalate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-4-dehydropantoate:NAD+ 4-oxidoreductase. Other names in common use include D-aldopantoate dehydrogenase, D-2-hydroxy-3,3-dimethyl-3-formylpropionate:diphosphopyridine, and nucleotide (DPN+) oxidoreductase. This enzyme participates in pantothenate and coa biosynthesis.