Rahul Sharma (Editor)

(R) 4 hydroxyphenyllactate dehydrogenase

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EC number  1.1.1.222
IntEnz  IntEnz view
ExPASy  NiceZyme view
CAS number  101754-02-3
BRENDA  BRENDA entry
KEGG  KEGG entry

In enzymology, a (R)-4-hydroxyphenyllactate dehydrogenase (EC 1.1.1.222) is an enzyme that catalyzes the chemical reaction

(R)-3-(4-hydroxyphenyl)lactate + NAD(P)+ 3-(4-hydroxyphenyl)pyruvate + NAD(P)H + H+

The 3 substrates of this enzyme are (R)-3-(4-hydroxyphenyl)lactate, NAD+, and NADP+, whereas its 4 products are 3-(4-hydroxyphenyl)pyruvate, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-3-(4-hydroxyphenyl)lactate:NAD(P)+ 2-oxidoreductase. Other names in common use include (R)-aromatic lactate dehydrogenase, and D-hydrogenase, D-aryllactate. This enzyme participates in tyrosine and phenylalanine catabolism.

References

(R)-4-hydroxyphenyllactate dehydrogenase Wikipedia


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